GUNJAN SUBEDI
TO VIEW THE FULL ARTICLE PLEASE CLICK HERE
Compression
is one of the most important step of
the Tablet formulation. It involves increase in mechanical strength of
the tablet by the application of the pressure (load) to reduce the bulk volume
by deformation of the particles and removal of the entrapped gases. Compression
results in the formation of compact solid dosage form which offer the
advantages of better handling, compactibility, increased stability, reduction
in volume etc. because of which, it can
be taken readily.
Various
approaches have been implemented for the formation of better tablet dosage form
by modifying various parameters and instrumentation in the compression machine
and compression process. The recent advances in compression through the incorporation of the various new
technologies like multi tip punches, Exchangeable Die Disc (EDD), turret and
die shells (DS), micro tab punches, external lubrication etc , provide various
other advances like Increased production rate, Reduced change over time,
Decreased cleaning time, Extended service life and improved quality in
production.
No comments:
Post a Comment